Application
Western blot analysis of C. elgans recombinant ces-2 fusion protein.| Product Name | ces-2 Antibody (ce-211) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-211 representing full length ces-2 of C. elegans origin |
| Modification Notes | Several proteins involved in regulating and executing programmed cell death have been identified in C. elegans. CED-2, which is similar to the human adaptor protein CrkII, as well as CED-5 and CED-7, which are orthologs of the mammalian DOCK180 and ABC transporter proteins, respectively, are involved in the engulfment of dying cells (1-3). CED-3, a member of the ICE protease/caspase family, and CED-4, a homolog of the mammalian Apaf-1 both promote apoptosis whereas CED-9, a homolog of the mammalian Bcl-2 protein, inhibits cell death (4-6). EGL-1 and CED-6 both function as death-promoting proteins, with CED-6 playing a role in the engulfment of apoptotic cells (7,8). CES-2 kills neurons by negatively regulating the protective activity of CES-1, thereby controlling the programmed deaths of specific neurons (9). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ces-2 of C. elegans origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-211 representing full length ces-2 of C. elegans origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-211 representing full length ces-2 of C. elegans origin |
Application
Western blot analysis of C. elgans recombinant ces-2 fusion protein.| Application Notes | recommended for detection of ces-2 of C. elegans origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
