Application
Western blot analysis of human TFB2M transfected 293T whole cell lysate.Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human intestine tissue showing cytoplasmic localization.| Product Name | TFB2M Antibody (X-23) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of TFB2M of human origin by WB, IP, IF, IHC(P) and ELISA |
| Modification Notes | TFB2M (transcription factor B2, mitochondrial), also known as NS5ATP5, Hkp1, Mitochondrial 12S rRNA dimethylase 2, Hepatitis C virus NS5A-transactivated protein 5 or mitochondrial Dimethyladenosine transferase 2, is a 396 amino acid mitochondrial protein that belongs to the rRNA adenine N(6)-methyltransferase family. Expressed ubiquitously, TFB2M is an S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. TFB2M is required for basal transcription of mitochondrial DNA and stimulates transcription independently of its methyltransferase activity. Compared to TFB1M, TFB2M has less methyltransferase activity but activates transcription of mitochondrial DNA more efficiently. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of TFB2M of human origin by WB IP IF IHC(P) and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of TFB2M of human origin by WB, IP, IF, IHC(P) and ELISA |
| Entrez Gene | 64216 |
|---|
Application
Western blot analysis of human TFB2M transfected 293T whole cell lysate.
Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human intestine tissue showing cytoplasmic localization.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
