Application
Western blot analysis of SMARCD3 expression in non-transfected: (A) and human SMARCD3 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of SMARCD3 expression in non-transfected 293T whole cell lysate.| Product Name | SMARCD3 Antibody (F-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against SMARCD3 of human origin |
| Modification Notes | SMARCD3 (SWI/SNF related, matrix associated, Actin dependent regulator of chromatin, subfamily d, member 3), also known as Rsc6p, CRACD3 or BAF60C (BRG1-associated factor 60C), is a member of the SMARCD family and contains one SWIB domain. Two isoforms, isoform 1 and isoform 2 exist due to alternative splicing events. Both isoforms are expressed in placenta, salivary gland, kidney, brain, trachea, uterus, prostate, testis, thyroid, spleen and heart, while isoform 1 is also expressed in adipose tissue and skeletal muscle. Localizing to the nucleus, SMARCD3 is a component of the ATP-dependent chromatin remodeling complex SNF/SWI and is believed to play a role in nucleosome remodeling. SMARCD3 also plays an important role in the regulation of muscle development. In mice, the silencing of the gene en-coding SMARCD3 leads to defects in heart morphogenesis. In addition, both isoforms of SMARCD3 directly interact with and function as coactivators for several transcription factors. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of SMARCD3 of mouse, rat, human, canine and zebra fish origin by WB, IP and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against SMARCD3 of human origin |
|---|---|
| Tissue Specificity | raised against SMARCD3 of human origin |
| Entrez Gene | 6604 |
|---|
Application
Western blot analysis of SMARCD3 expression in non-transfected: (A) and human SMARCD3 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of SMARCD3 expression in non-transfected 293T whole cell lysate.| Application Notes | recommended for detection of SMARCD3 of mouse, rat, human, canine and zebra fish origin by WB, IP and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
