Application
Western blot analysis of CELF3 expression in Jurkat whole cell lysate.| Product Name | CELF3 Antibody (G-25) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against CELF3 of human origin |
| Modification Notes | CELF3 (CUG-BP- and ETR-3-like factor 3), also known as TNRC4 (trinucleotide repeat containing 4), CAGH4 (CAG repeat protein 4), ETR-1 (ELAV-type RNA-binding protein 1), ERDA4 (expanded repeat domain protein CAG/CTG 4) or BRUNOL1 (Bruno-like protein 1), is an RNA-binding protein that belongs to the CELF/BRUNOL family of proteins. Expressed specifically in brain, CELF3 contains three RRM (RNA recognition motif) domains (two at the N-terminus and one at the C-terminus) and localizes to the nucleus and the cytoplasm. As is characteristic of the CELF/BRUNOL family, CELF3 binds specifically to muscle-specific splicing enhancer (MSE)-containing RNAs and is believed to play a role in the regulation of pre-mRNA alternative splicing. In addition, CELF3 may participate in translation and mRNA editing. Due to alternative splicing events, CELF3 exists as three isoforms. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of CELF3 of mouse, rat, human and canine origin by WB, IP and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against CELF3 of human origin |
|---|---|
| Tissue Specificity | raised against CELF3 of human origin |
| Entrez Gene | 11189 |
|---|
Application
Western blot analysis of CELF3 expression in Jurkat whole cell lysate.| Application Notes | recommended for detection of CELF3 of mouse, rat, human and canine origin by WB, IP and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
