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LTK Antibody (N-term)

Catalog Number:OM173684
OM173684
Discount Price
OM173684-100ul
1~2 Week
100ul
OM173684-50ul
50ul
OM173684-20ul
20ul
1~2 Week
Product Profile
Product Name LTK Antibody (N-term)
Antibody Type Primary Antibodies
Antigen Alias LTK; TYK1; Leukocyte tyrosine kinase receptor; Protein tyrosine kinase 1
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WB
WB:1:100~500
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms TYK1
Alternative Names LTK
TYK1
Leukocyte tyrosine kinase receptor
Protein tyrosine kinase 1
Molecular Weight(MW) 91681 Da
Function Orphan receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport
Tissue Specificity Expressed in non-hematopoietic cell lines and T- and B-cell lines
Cellular Localization Membrane; Single-pass type I membrane protein
Database Links
Entrez Gene 4058
Application

Application

The anti-LTK Pab (Cat. #AP7658a) is used in Western blot to detect LTK in placenta cell lysate.
Application Notes WB:1:100~500
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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