Application
LYPLA3 Antibody (C-term) (Cat. #AP11706b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the LYPLA3 antibody detected the LYPLA3 protein (arrow).Application
LYPLA3 Antibody (C-term) (Cat. #AP11706b)immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of LYPLA3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
Confocal immunofluorescent analysis of LYPLA3 Antibody (C-term)(Cat#AP11706b) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).| Product Name | LYPLA3 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PLA2G15; LYPLA3; Group XV phospholipase A2; 1-O-acylceramide synthase; LCAT-like lysophospholipase; Lysophospholipase 3; Lysosomal phospholipase A2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | LYPLA3 |
|---|---|
| Alternative Names | PLA2G15 LYPLA3 Group XV phospholipase A2 1-O-acylceramide synthase LCAT-like lysophospholipase Lysophospholipase 3 Lysosomal phospholipase A2 |
| Molecular Weight(MW) | 46658 Da |
| Function | Has transacylase and calcium-independent phospholipase A2 activity. Catalyzes the formation of 1-O-acyl-N- acetylsphingosine and the concomitant release of a lyso- phospholipid (By similarity). May have weak lysophospholipase activity |
| Tissue Specificity | Highly expressed in heart, placenta, skeletal muscle, kidney and pancreas. Detected at lower levels in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes |
| Cellular Localization | Lysosome (By similarity). Secreted. |
| Entrez Gene | 23659 |
|---|---|
| Nucleotide Accession | NP_036452.1 |
Application
LYPLA3 Antibody (C-term) (Cat. #AP11706b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the LYPLA3 antibody detected the LYPLA3 protein (arrow).
Application
LYPLA3 Antibody (C-term) (Cat. #AP11706b)immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of LYPLA3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
Confocal immunofluorescent analysis of LYPLA3 Antibody (C-term)(Cat#AP11706b) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
