Application
LZTS2 Antibody (C-term) (Cat. #AP13002b) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the LZTS2 antibody detected the LZTS2 protein (arrow).| Product Name | LZTS2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LZTS2; KIAA1813; LAPSER1; Leucine zipper putative tumor suppressor 2; Protein LAPSER1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1813 LAPSER1 |
|---|---|
| Alternative Names | LZTS2 KIAA1813 LAPSER1 Leucine zipper putative tumor suppressor 2 Protein LAPSER1 |
| Molecular Weight(MW) | 72759 Da |
| Function | Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin |
| Tissue Specificity | Highly expressed in prostate and testis, and at slightly lower levels in spleen, thymus, uterus, small intestine and colon |
| Cellular Localization | Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Note=Localized to the centrosome throughout the cell cycle. Localized to the midbody in cells undergoing cytokinesis |
| Entrez Gene | 84445 |
|---|---|
| Nucleotide Accession | NP_115805.1 |
Application
LZTS2 Antibody (C-term) (Cat. #AP13002b) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the LZTS2 antibody detected the LZTS2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
