Application
A. Western blot analysis on 5 ng of recombinant protein using anti-M-CSF RabMAb (Cat. #AJ1466a), dilution 1:50,000.Application
B. Immunohistochemical staining of paraffin-embedded human tonsils using anti-M-CSF RabMAb (Cat. #AJ1466a).| Product Name | M-CSF Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CSF1, Processed macrophage colony-stimulating factor 1, Lanimostim |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP1179Y |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CSF1 Processed macrophage colony-stimulating factor 1 Lanimostim |
|---|---|
| Molecular Weight(MW) | 60179 Da |
| Function | Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration Plays a role in lipoprotein clearance |
| Tissue Specificity | A synthetic peptide corresponding to residues on human M-CSF was used as an immunogen. |
| Cellular Localization | Cell membrane; Single-pass membrane protein. |
| Entrez Gene | 1435 |
|---|
Application
A. Western blot analysis on 5 ng of recombinant protein using anti-M-CSF RabMAb (Cat. #AJ1466a), dilution 1:50,000.
Application
B. Immunohistochemical staining of paraffin-embedded human tonsils using anti-M-CSF RabMAb (Cat. #AJ1466a).| Application Notes | WB:1:500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
