Application
MAEA Antibody (N-term) (Cat. #AP17927a) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the MAEA antibody detected the MAEA protein (arrow).| Product Name | MAEA Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MAEA; EMP; Macrophage erythroblast attacher; Cell proliferation-inducing gene 5 protein; Erythroblast macrophage protein; Human lung cancer oncogene 10 protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | EMP |
|---|---|
| Alternative Names | MAEA EMP Macrophage erythroblast attacher Cell proliferation-inducing gene 5 protein Erythroblast macrophage protein Human lung cancer oncogene 10 protein |
| Molecular Weight(MW) | 45287 Da |
| Function | Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA- mediated contact inhibits erythroid cells apoptosis. Participates to erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events |
| Tissue Specificity | Ubiquitous. |
| Cellular Localization | Nucleus matrix. Cell membrane. Cytoplasm, cytoskeleton. Note=Localized as nuclear speckled-like pattern |
| Entrez Gene | 10296 |
|---|---|
| Nucleotide Accession | NP_001017405.1 NP_005873.2 |
Application
MAEA Antibody (N-term) (Cat. #AP17927a) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the MAEA antibody detected the MAEA protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
