Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human stomach tissue showing cytoplasmic staining of glandular cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.Application
Western blot analysis of AEBP1 expression in mouse heart tissue extract.| Product Name | AEBP1 Antibody (H-164) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 995-1158 mapping at the C-terminus of AEBP1 of human origin |
| Modification Notes | Aortic carboxypeptidase-like protein (ACLP), of which adipocyte enhancer binding protein 1 (AEBP1) is an isoform, is a transcriptional repressor with carboxypeptidase activity that is expressed in vascular smooth muscle cells, and at lower levels in adipose and osteoblastic cells. ACLP contains a signal peptide sequence, a lysine- and proline-rich repeating motif, a discoidin-like protein and a carboxypeptidase-like domain. ACLP is secreted into the extracellular matrix and may play a role in abdominal wall development and dermal wound healing. Additionally, ACLP is downregulated during adipogenesis and upregulated during vascular smooth muscle cell differentiation, suggesting a possible role in tissue development. AEBP1, which may function as a transcriptional repressor, is a truncated form of ACLP which specifically lacks a 380 amino acid N-terminal sequence. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of AEBP1 and the ACLP isoform of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 995-1158 mapping at the C-terminus of AEBP1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 995-1158 mapping at the C-terminus of AEBP1 of human origin |
| Entrez Gene | 165 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human stomach tissue showing cytoplasmic staining of glandular cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Application
Western blot analysis of AEBP1 expression in mouse heart tissue extract.| Application Notes | recommended for detection of AEBP1 and the ACLP isoform of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
