epitope corresponding to amino acids 19-318 mapping near the N-terminus of BRF2 of human origin
Modification Notes
Human cells contain two types of RNA polymerase III transcription factor (TFIIIB), BRF1 and BRF2. BRF1, functions in recruitment of RNA polymerase III to the promoter for multiple rounds of transcription. BRF1 precisely positions TFIIIB on the upstream promoter-less DNA by creating stable protein-protein interactions with TATA-binding protein (TBP), another component of TFIIIB. BRF2, is recruited to type 3 promoters such as the human U6 snRNA promoter. It differs from BRF1-TFIIIB in that it contains the TFIIB-related factor BRF2 instead of Brf1 and its three components do not form a stable complex.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of BRF2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 19-318 mapping near the N-terminus of BRF2 of human origin
Tissue Specificity
epitope corresponding to amino acids 19-318 mapping near the N-terminus of BRF2 of human origin
recommended for detection of BRF2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.