| Product Name | POU6F2 Antibody (H-145) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 9-153 mapping near the N-terminus of POU6F2 of human origin |
| Modification Notes | Tissue-restricted POU domain transcription factors play roles in cellular differentiation and the development of several organs. POU6F2 (POU class 6 homeobox 2), also known as RPF-1 (retina-derived POU domain factor 1), WT5 or WTSL, is a 683 amino acid nuclear protein expressed exclusively in the central nervous system (CNS). POU6F2 localizes to neurons of the dorsal hypothalamus, as well as retinal cells, where it is thought to function as a transcription factor during early amacrine and ganglion cell differentiation. Existing as two alternatively spliced isoforms, POU6F2 contains one homeobox DNA-binding domain, a single POU-specific domain, and is encoded by a gene that maps to human chromosome 7p14.1. POU6F2 defects are associated with Wilms tumor 5 (WT5). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of POU6F2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 9-153 mapping near the N-terminus of POU6F2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 9-153 mapping near the N-terminus of POU6F2 of human origin |
| Entrez Gene | 11281 |
|---|
| Application Notes | recommended for detection of POU6F2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
