epitope corresponding to amino acids 1-68 representing full length β-defensin 1 of human origin
Modification Notes
∫-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, ∫-defensins are developmentally regulated. Research indicates that human ∫-defensin 1 may contribute to the antimicrobial activity of airway surface fluid and may play a role in the mucosal defenses of the lung. Human ∫-defensin 1 shares homology with other ∫-defensins from human blood filtrate and is also present in nanomolar concentrations in human plasma. In addition to the antimicrobial activity of human airway epithelia, ∫-defensin 1 may play a role in the mucosal defenses of the lung.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of β-defensin 1 of human origin by WB, IP, IF and ELISA:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-68 representing full length &beta -defensin 1 of human origin
Tissue Specificity
epitope corresponding to amino acids 1-68 representing full length β-defensin 1 of human origin