| Product Name | USP4 Antibody (H-72) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 708-779 mapping within an internal region of USP4 of human origin |
| Modification Notes | The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP4 (ubiquitin-specific-processing protease 4), also known as ubiquitin carboxyl-terminal hydrolase 4, UNP or UNPH (ubiquitous nuclear protein homolog), is a 963 amino acid nucleocytoplasmic protein that belongs to the peptidase C19 family. USP4 binds to the C-terminus of Adenosine A2A-R, a Gs-coupled receptor, and enhances cell surface expression of the functionally active receptor. USP4 contains one DUSP domain and exists as two isoforms due to alternative splicing. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of USP4 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 708-779 mapping within an internal region of USP4 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 708-779 mapping within an internal region of USP4 of human origin |
| Entrez Gene | 7375 |
|---|
| Application Notes | recommended for detection of USP4 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
