| Product Name | TBC1D8 Antibody (H-63) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 701-763 mapping within an internal region of TBC1D8 of human origin |
| Modification Notes | GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in downregulation of their active form. TBC1D8 (TBC1 domain family member 8), also known as VRP (Vascular Rab-GAP/TBC-containing protein), AD3 or HBLP1, is an 897 amino acid protein that is thought to function as a GTPase-activator for Rab proteins. TBC1D8 contains one GRAM domain and one Rab-GAP TBC domain, the latter of which is a highly conserved 200 amino acid motif that conveys the catalytic activity of GTPase-activating proteins. The gene encoding TBC1D8 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TBC1D8 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 701-763 mapping within an internal region of TBC1D8 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 701-763 mapping within an internal region of TBC1D8 of human origin |
| Entrez Gene | 11138 |
|---|
| Application Notes | recommended for detection of TBC1D8 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
