| Product Name | PPP2R5E Antibody (H-82) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 183-264 mapping within an internal region of PPP2R5E of human origin |
| Modification Notes | In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. PPP2R5E (protein phosphatase 2, regulatory subunit B', epsilon isoform) is a 467 amino acid protein that localizes to the cytoplasm and exists as an isoform of the B regulatory subunit within the PP multimeric complex. Functioning as a regulatory subunit, PPP2R5E is thought to modulate both the catalytic activity and the substrate specificity of the PP holoenzyme and may also be responsible for the localization of the complex to subcellular compartments. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of PPP2R5E of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 183-264 mapping within an internal region of PPP2R5E of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 183-264 mapping within an internal region of PPP2R5E of human origin |
| Entrez Gene | 5529 |
|---|
| Application Notes | recommended for detection of PPP2R5E of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
