| Product Name | CCDC98 Antibody (H-100) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 33-132 mapping within an internal region of CCDC98 of human origin |
| Modification Notes | Coiled-coil domain-containing protein 98 (CCDC98), also known as FAM175A and ABRA1, is a 409 amino acid member of the FAM175 family. Functioning as a breast cancer-1 (BRCA1) interacting protein, CCDC98 colocalizes with BRCA1 to play a role in DNA repair. BRCA1 is a protein that is recruited to DNA breaks and participates in checkpoint regulations, specifically during S phase and at the G2/M transition. CCDC98 acts upstream of BRCA1 and regulates BRCA1 in DNA repair and checkpoint regulations in a phosphorylation-dependent manner. Moreover, CCDC98 has been shown to be necessary for the formation of BRCA1 foci in response to ionizing radiation. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CCDC98 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 33-132 mapping within an internal region of CCDC98 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 33-132 mapping within an internal region of CCDC98 of human origin |
| Entrez Gene | 84142 |
|---|
| Application Notes | recommended for detection of CCDC98 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
