epitope corresponding to amino acids 1-80 representing full length CD24 of human origin
Modification Notes
CD24 is a GPI-linked membrane sialoglycoprotein that is expressed on pro-B, pre-B and mature B cells, and its expression is decreased after B cell activation. CD24 is also found on granulocytes and a small fraction of thymocytes and neuroblastomas, but not on plasma cells. CD24 may play a role in the regulation of B cell proliferation and differentiation. CD24 is expressed in hematological malignancies as well as in a large variety of solid tumors. A shift from apical localization to cytoplasmic staining of CD24 is a surrogate marker of stromal invasion in ovarian serous tumors of borderline malignancy. CD24 protein can be a B cell differentiation marker that is expressed on mature resting B cells and disappears upon stimulation.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of CD24 of mouse, rat and human origin by WB, IP, IF and ELISA:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-80 representing full length CD24 of human origin
Tissue Specificity
epitope corresponding to amino acids 1-80 representing full length CD24 of human origin