| Product Name | COL8A2 Antibody (H-45) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 531-575 mapping within an internal region of Collagen α2 type VIII of human origin |
| Modification Notes | COL8A2 (collagen alpha-2(VIII) chain ), also known as endothelial collagen, is a 703 amino acid secreted protein. COL8A2 is a major component of the Descemet membrane (basement membrane) of corneal endothelial cells. COL8A2 can form homodimers as well as heterodimers with COL8A1. Defects in COL8A2 are a cause for posterior polymorphous corneal dystrophy (PPCD) and Fuchs endothelial corneal dystrophy (FECD), both being disorders with visual impairment occurring in adulthood. COL8A2 is also the cause of posterior polymorphous corneal dystrophy 2 (PPCD2), a rare familial disorder that occurs from birth onwards. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Collagen α2 type VIII of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 531-575 mapping within an internal region of Collagen &alpha 2 type VIII of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 531-575 mapping within an internal region of Collagen α2 type VIII of human origin |
| Entrez Gene | 1296 |
|---|
| Application Notes | recommended for detection of Collagen α2 type VIII of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
