| Product Name | BMCP1/KMCP1 Antibody (H-85) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Members of the mitochondrial carrier family transport a variety of metabolites across the inner mitochondrial membrane. Brain mitochondrial carrier protein 1 (BMCP1), also designated uncoupling protein 5 (UCP5) or solute carrier family 25 member 14 (SLC25A14), is a 325 amino acid proton channel carrier protein that is not coupled to oxidative phosphorylation. BMCP1 is located in the inner membrane of mitochondria and is linked to the generation of heat. Like other UCPs, BMCP1 facilitates the transfer of anions from the inner to the outer mitochondrial membrane, as well as the return transfer of protons from the outer to the inner mitochondrial membrane. Kidney mitochondrial carrier protein-1 (KMCP1), also designated solute carrier family 25 member 30 (SLC25A30), is a 291 amino acid multi-pass membrane protein that localizes to mitochondria and is highly expressed in kidney cortex. KMCP1 is important during increased mitochondrial metabolism and is up-regulated in response to cellular oxidative damage. KMCP1 is highly homologous to BMCP1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of all isoforms of BMCP1 (UCP5) and KMCP1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 211-295 mapping near the C-terminus of BMCP1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 211-295 mapping near the C-terminus of BMCP1 of human origin |
| Application Notes | recommended for detection of all isoforms of BMCP1 (UCP5) and KMCP1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
