Application
Western blot analysis of RBM4 expression in non-transfected (A) and human RBM4 transfected (B) whole cell lysates.Application
Western blot analysis of RBM4 expression in HeLa nuclear extract (A) and A-431 whole cell lysate (B).Application
Western blot analysis of RBM4 expression in Jurkat whole cell lysate.| Product Name | RBM4 Antibody (H-100) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | RBM4 (RNA binding motif protein 4), also known as LARK, RBM4A, ZCRB3A or ZCCHC21, is a 364 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one CCHC-type zinc finger and two RRM domains. Expressed ubiquitously, RBM4 interacts with Importin-12 (an association which results in the nuclear import of RBM4) and is thought to play a role in alternative splice site selection during pre-mRNA processing. RBM4 is down-regulated in patients affected with fetal Down syndrome (DS), suggesting that RBM4 may be involved in the regulation of normal brain development. Multiple isoforms of RBM4 exist due to alternative splicing events. RBM4B (RNA binding motif protein 4B), also known as RBM30, is a 359 amino acid protein that functions in a similar manner to RBM4 and is involved in the regulation of alternative splicing. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of RBM4A and RBM4B of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-100 mapping at the N-terminus of RBM4A of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-100 mapping at the N-terminus of RBM4A of human origin |
| Entrez Gene | 5936 |
|---|
Application
Western blot analysis of RBM4 expression in non-transfected (A) and human RBM4 transfected (B) whole cell lysates.
Application
Western blot analysis of RBM4 expression in HeLa nuclear extract (A) and A-431 whole cell lysate (B).
Application
Western blot analysis of RBM4 expression in Jurkat whole cell lysate.| Application Notes | recommended for detection of RBM4A and RBM4B of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
