epitope corresponding to amino acids 51-210 mapping near the N-terminus of FTSJ1 of human origin
Modification Notes
FTSJ1 (FtsJ homolog 1), also known as putative ribosomal RNA methyltransferase 1, rRNA (uridine-2'-O-)-methyltransferase, MRX44, JM23, SPB1, MRX9, TRM7 or CDLIV, is a 329 amino acid nucleolar protein belonging to the RlmE family and methyltransferase superfamily. Expressed in adult thalamus, hippocampus, amygdala, corpus callosum and caudate nucleus, as well as fetal kidney, lung, liver, brain and lung, FTSJ1 plays a role in rRNA modification and processing. FTSJ1 exists as multiple spliced isoforms which are encoded by a gene located on human chromosome Xp11.23. Notably, defects in the gene encoding FTSJ1 are the cause of mental retardation X-linked type 44 (MRX44) and nonsyndromic X-linked mental retardation (MRX9).
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of FTSJ1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 51-210 mapping near the N-terminus of FTSJ1 of human origin
Tissue Specificity
epitope corresponding to amino acids 51-210 mapping near the N-terminus of FTSJ1 of human origin
Application
Application
Western blot analysis of FTSJ1 expression in HeLa (A) and SK-N-MC (B) whole cell lysates.
Application Notes
recommended for detection of FTSJ1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.