Application
Western blot analysis of CESK1 expression in HeLa (A), Jurkat (B), U-937 (C), IMR-32 (D), A-673 (E) and CCRF-CEM (F) whole cell lysates.| Product Name | CESK1 Antibody (N-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | recommended for detection of CESK1 and CCT8L1 of human origin by WB, IP, IF and ELISA |
| Modification Notes | CESK1, also known as CCT8L2 (chaperonin containing TCP1, subunit 8 theta-like 2), is a 557 amino acid protein that localizes to the cytoplasm and is thought to function as a molecular chaperone, possibly assisting protein folding after ATP hydrolysis. CESK1 belongs to the TCP-1 chaperonin family and is encoded by a gene which maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein Bcr-Abl, a potent cell proliferation activator found in several types of leukemias. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIPWB |
| WB:1:200-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the N-terminus of CESK1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the N-terminus of CESK1 of human origin |
| Entrez Gene | 150160 |
|---|
Application
Western blot analysis of CESK1 expression in HeLa (A), Jurkat (B), U-937 (C), IMR-32 (D), A-673 (E) and CCRF-CEM (F) whole cell lysates.| Application Notes | WB:1:200-1:2000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
