| Product Name | Repo-Man Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The eukaryotic cell division cycle consists of a number of gene-controlled sequences that involve cyclin dependent kinases (Cdks) and cell division cycle (Cdc) proteins. Repo-man, also known as CDCA2 (cell division cycle associated 2), is a 1,024 amino acid protein that localizes to different areas within the nucleus in a phosphorylation-dependent manner. Expressed ubiquitously, Repo-Man functions to regulate mitotic chromosome structure and is specifically required to maintain compact chromosomal architecture in the absence of condensins during anaphase. Due to its ability to maintain proper chromosomal structure and function, Repo-man plays a key role in cell cycle progression and, if upregulated, may be involved in tumor formation and metastasis. Two isoforms of Repo-man exist due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Repo-Man of human origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-300 mapping at the N-terminus of Repo-Man of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-300 mapping at the N-terminus of Repo-Man of human origin |
| Entrez Gene | 157313 |
|---|
| Application Notes | recommended for detection of Repo-Man of human origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
