Western blot analysis of SLC35C2 expression in mouse liver (A) and mouse prostate (B) tissue extracts and Hep G2 (C) and MIA PaCa-2 (D) whole cell lysates.
SLC35C2 (solute carrier family 35, member C2), also known as C20orf5, OVCOV1 or CGI-15, is a 365 amino acid multi-pass membrane protein that belongs to the TPT transporter family and exists as multiple alternatively spliced isoforms. Expressed ubiquitously and functionally induced in hypoxic trophoblast cells, SLC35C2 plays a role in the cellular response to tissue hypoxia and is thought to be involved in the pathogenesis of ovarian cancer. The gene encoding SLC35C2 maps to human chromosome 20, which houses over 600 genes some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of SLC35C2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of SLC35C2 of human origin
Tissue Specificity
epitope mapping within an internal region of SLC35C2 of human origin
Western blot analysis of SLC35C2 expression in mouse liver (A) and mouse prostate (B) tissue extracts and Hep G2 (C) and MIA PaCa-2 (D) whole cell lysates.
Application Notes
recommended for detection of SLC35C2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.