| Product Name | YTHDF2 Antibody (H-65) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The YTH domain family protein family (YTHDF) includes YTHDF1, YTHDF2 and TYHDF3. YTHDF2 (YTH domain family, member 2), also designated high-glucose-regulated protein 8, CLL-associated antigen KW-14 or renal carcinoma antigen NY-REN-2, is a 579 amino acid protein that also contains one YTH domain and exists as two alternatively spliced isoforms. Expressed in pancreas, testis and placenta, YTHDF2 has been identified as a translocation partner gene for RUNX1 and is encoded by a gene mapping to human chromosome 1p35.3. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of YTHDF2 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with YTHDF1 or YTHDF3 also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 181-245 mapping within an internal region of YTHDF2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 181-245 mapping within an internal region of YTHDF2 of human origin |
| Entrez Gene | 51441 |
|---|
| Application Notes | recommended for detection of YTHDF2 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with YTHDF1 or YTHDF3 also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
