| Product Name | KiSS-1 Antibody (FL-145) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | KiSS-1 is a 145 amino acid human protein that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The human KiSS-1 gene maps to chromosome 1q32 and consists of four exons. Transcripts for human KiSS-1 are predominantly expressed in the brain and placenta. KiSS-1 protein contains a polyproline-rich domain (SH3 ligand) and a putative protein kinase C-alpha phosphorylation site. KiSS-1 may regulate events downstream of cell-matrix adhesion in mechanisms involving cytoskeletal reorganization. Expression of KiSS-1 reduces the level of NFkappaB p50/p65 binding to the MMP-9 promoter and correlates with diminished expression of MMP-9 (also designated 92 kDa type IV collagenase or gelatinase B). KiSS-1 displays agonist activity on the orphan G protein-coupled receptor GPR54. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of KiSS-1 of human origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-145 representing full length KiSS-1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-145 representing full length KiSS-1 of human origin |
| Entrez Gene | 3814 |
|---|
| Application Notes | recommended for detection of KiSS-1 of human origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
