| Product Name | Bex1/2 Antibody (H-72) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The brain-expressed X-linked (Bex) family of proteins is expressed in the central nervous system, with highest levels detected in cerebellum, temporal lobe and pituitary tissues. Bex1 plays an important role in neuronal differentiation in response to nerve growth factor (NGF), as well as in cell cycle progression. Bex1 is a highly ubiquitinated protein and acts as a link between the cell cycle and neurotrophic factor signaling. Bex2 interacts with LMO2, thereby regulating the transcriptional activity of a DNA-binding complex. Bex1 and Bex 2 are widely expressed outside of the central nervous system with high expression in the liver. Bex1 and Bex2 shuttle between the cytoplasm and the nucleus. Though the role of Bex1 is largely unknown, it may function by coordinating internal cellular states with the ability of cells to respond to external signals. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Bex1 and Bex2 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 39-110 mapping within an internal region of Bex1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 39-110 mapping within an internal region of Bex1 of human origin |
| Entrez Gene | 55859 |
|---|
| Application Notes | recommended for detection of Bex1 and Bex2 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
