Application
Western blot analysis of mGluR-2/3 expression in rat hippocampal tissue extract.| Product Name | mGluR-2/3 Antibody (F-25) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The mGluR proteins (metabotropic glutamate receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G-proteins with opposing regulation of adenylate cyclase pathways. mGluR-2 (also known as GRM2) and mGluR-3 (also known as GRM3), two members of the mGluR family, are multi-pass membrane proteins that are thought to interact with GRASP, possibly acting as receptors for glutamate. Additionally, they may also be involved in the regulation of neurotransmission suppression and in synaptogenesis or synaptic stabilization. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIF |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of mGluR-2/3 of mouse rat human and zebrafish origin by WB IP and IF also reactive with additional species including bovine and canine |
|---|---|
| Tissue Specificity | recommended for detection of mGluR-2/3 of mouse, rat, human and zebrafish origin by WB, IP and IF; also reactive with additional species, including bovine and canine |
| Entrez Gene | 2912 |
|---|
Application
Western blot analysis of mGluR-2/3 expression in rat hippocampal tissue extract.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
