Neutral amino acid transporter proteins, also designated alanine/serine/cysteine/threonine transporters (ASCT), belong to the sodium dicarboxylate (SDF) symporter family of proteins. The members of this family of proteins are multi-pass membrane-bound proteins that act as transporters for threonine, alanine, serine and cysteine. ASCT1 and ASCT2 have been shown to exhibit sodium dependence. ASCT1 is expressed in most tissues, but highest expression has been detected in muscle, brain and pancreas. The highest levels of ASCT2 expression are found in placenta, kidney, pancreas, muscle and intestine.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFIHCELISA
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of ASCT2 of mouse rat and human origin by WB IP IF IHC(P) and ELISA also reactive with additional species including canine
Tissue Specificity
recommended for detection of ASCT2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including canine