SPATA13 (spermatogenesis associated 13), also known as ASEF2, is a 652 amino acid protein that may be involved in the regulation of spermatogenesis. SPATA13 contains a DH (DBL-homology) domain and a PH (pleckstrin-homology) domain, both of which are found in a variety of proteins that are involved in gene expression, membrane trafficking, growth factor signaling or cellular transformation. The gene encoding SPATA13 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. Trisomy 13, also known as Patau syndrome, is a deadly syndrome associated with chromosome 13. The few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of SPATA13 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with SPATA19 and SPATA20.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping near the N-terminus of SPATA13 of human origin
Tissue Specificity
epitope mapping near the N-terminus of SPATA13 of human origin