Application
Western blot analysis of RRP12 expression in HeLa whole cell lysate (A) and HeLa (B) and Jurkat (C) nuclear extracts.| Product Name | RRP12 Antibody (E-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Ribosomes are the organelles that catalyze protein synthesis. Each ribosomes consists of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RRP12 (ribosomal RNA processing 12) is a 1,297 amino acid single-pass membrane protein that participates in ribosomal assembly. Expressed in testis and ovary, RRP12 belongs to the RRP12 family and localizes to the nucleus. RRP12 may be involved in coupling the control of ribosome production to the regulation of other cellular processes during cell cycle progression. In conjunction with Dim2, RRP12 is thought to be involved in the nucleocytoplasmic translocation of pre-ribosomes during ribosome assembly. RRP12 exists two alternatively spliced isoforms and is encoded by a gene located on human chromosome 10q24.1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of RRP12 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other RRP family members also reactive with additional species, including equine, canine, porcine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of RRP12 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of RRP12 of human origin |
| Entrez Gene | 23223 |
|---|
Application
Western blot analysis of RRP12 expression in HeLa whole cell lysate (A) and HeLa (B) and Jurkat (C) nuclear extracts.| Application Notes | recommended for detection of RRP12 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other RRP family members also reactive with additional species, including equine, canine, porcine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
