Application
Western blot analysis of TSNAXIP1 expression in non-transfected: (A) and human TSNAXIP1 transfected: (B) 293T whole cell lysates and mouse lung tissue extract (C).| Product Name | TSNAXIP1 Antibody (H-198) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | TSNAXIP1 (Translin-associated factor X-interacting protein 1) is a 658 amino acid gene product believed to interact with TSNAX (Translin-associated factor X). TSNAX, a translin family protein, is often found as a sumoylated perinuclear association factor. The TSNAX gene is located immediately upstream of DISC1 (Disrupted-in-Schizophrenia-1) and together are candidate genes in relation to psychiatric illness, as one transcript variation may result from intergenic splicing to encode a novel TSNAX-DISC1 fusion protein. The gene encoding TSNAXIP1 is located on Chromosome 16 which encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TSNAXIP1 of mouse, rat and human origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 63-260 mapping within an internal region of TSNAXIP1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 63-260 mapping within an internal region of TSNAXIP1 of human origin |
| Entrez Gene | 55815 |
|---|
Application
Western blot analysis of TSNAXIP1 expression in non-transfected: (A) and human TSNAXIP1 transfected: (B) 293T whole cell lysates and mouse lung tissue extract (C).| Application Notes | recommended for detection of TSNAXIP1 of mouse, rat and human origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
