Application
Immunofluorescence staining of formalin-fixed Hep G2 cells showing membrane localization.Application
Western blot analysis of LRTM1 expression in K-562 (A), Hep G2 (B), A-431 (C) and HEL 92.1.7 (D) whole cell lysates.| Product Name | LRTM1 Antibody (P-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Leucine-rich repeats (LRRs) are 20-30 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in the genes encoding LRR-containing proteins. LRTM1 (Leucine-rich repeat and transmembrane domain-containing protein 1) is a 345 amino acid single pass transmembrane protein that contains five LRRs. The gene encoding LRTM1 maps to chromosome 3, which spans 200 million base pairs and encodes between 1,100 and 1,500 genes. There are two isoforms of LRTM1 which are produced as a result of alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of LRTM1 of human origin by WB, IP, IF and ELISA non cross-reactive with family member LRTM2 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an extracellular domain of LRTM1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an extracellular domain of LRTM1 of human origin |
| Entrez Gene | 57408 |
|---|
Application
Immunofluorescence staining of formalin-fixed Hep G2 cells showing membrane localization.
Application
Western blot analysis of LRTM1 expression in K-562 (A), Hep G2 (B), A-431 (C) and HEL 92.1.7 (D) whole cell lysates.| Application Notes | recommended for detection of LRTM1 of human origin by WB, IP, IF and ELISA non cross-reactive with family member LRTM2 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
