| Product Name | TRPM3 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The transient receptor potential (TRP) protein family consists of a diverse group of cation channels functioning in a variety of homeostatic and regulatory pathways. Four subfamilies exist, based on channel domain homology, not activating stimuli: C type (canonical or classical), V type (vanilloid receptor related), M type (melastatin related) and P type (PKD). TRPM3 (transient receptor potential cation channel subfamily M member 3), also known as long transient receptor potential channel 3v and melastatin 2, is a 1,732 amino acid multi-pass membrane protein that is a member of the M-type subfamily and is closely related to MLSN1 (melastatin 1), also known as TRPM1. TRPM3 functions as a calcium channel that mediates entry of cal-cium ion into the cell. A decrease in extracellular osmolarity, depletion of stored calcium and muscarinic receptor activation result in an increase of TRPM3 channel activity. Nine isoforms of TRPM3 are produced as a result of alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TRPM3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1433-1732 mapping at the C-terminus of TRPM3 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1433-1732 mapping at the C-terminus of TRPM3 of human origin |
| Entrez Gene | 80036 |
|---|
| Application Notes | recommended for detection of TRPM3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
