Application
Western blot analysis of GREB1 expression in DU 145 whole cell lysate.| Product Name | GREB1 Antibody (N-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | GREB1 (Gene regulated in breast cancer 1 protein), is a 1949 amino acid single-pass membrane protein that is expressed in proliferating prostatic tissue and prostate cancer and is strongly upregulated by 17∫-estradiol. It is suggested that GREB1 may have an important role in hormone-responsive tissues and cancer. Regulated by androgens, GREB1 is critically involved in the estrogen induced proliferation in breast cancer cells. GREB1 is a potential clinical marker for response to endocrine therapy and as a potential therapeutic target. Four isoforms exists due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of GREB1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of GREB1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of GREB1 of human origin |
| Entrez Gene | 9687 |
|---|
Application
Western blot analysis of GREB1 expression in DU 145 whole cell lysate.| Application Notes | recommended for detection of GREB1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
