With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. The KIAA0141 gene product has been provisionally designated KIAA0141 pending further characterization.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIFELISA
recommended for detection of 0610009O20Rik of mouse origin, KIAA0141 of human origin and RGD735029 of rat origin by WB, IF and ELISA also reactive with additional species, including equine, canine and porcine
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of KIAA0141 of human origin
Tissue Specificity
epitope mapping within an internal region of KIAA0141 of human origin
recommended for detection of 0610009O20Rik of mouse origin, KIAA0141 of human origin and RGD735029 of rat origin by WB, IF and ELISA also reactive with additional species, including equine, canine and porcine
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.