Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The FAM154A gene product has been provisionally designated FAM154A pending further characterization.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIFELISA
recommended for detection of FAM154A of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with FAM154B also reactive with additional species, including equine
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of FAM154A of human origin
Tissue Specificity
epitope mapping within an internal region of FAM154A of human origin
Western blot analysis of FAM154A expression in non-transfected: (A) and human FAM154A transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of FAM154A of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with FAM154B also reactive with additional species, including equine
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.