Application
Western blot analysis of SCGN expression in non-transfected: (A) and mouse SCGN transfected: (B) 293T whole cell lysates.| Product Name | SCGN Antibody (H-91) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | SCGN, also known as Secretagogin, CALBL, setagin or SECRET, is a 276 amino acid cytoplasmic protein that contains six EF-hand domains and is related to the calicium-binding proteins Calretinin and Calbindin D28K. Expressed in a variety of tissues including stomach, thyroid, colon, brain and neuroendocrine cells, SCGN is thought to be involved in cell proliferation and KCl (potassium chloride)-mediated calcium flux events. Through its interaction with KCl and its subsequent ability to modulate calcium storage pools within the cell, SCGN may function to negatively control growth and differentiation rates and, thus, indirectly inhibit cell replication. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SCGN of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 186-276 mapping at the C-terminus of SCGN of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 186-276 mapping at the C-terminus of SCGN of human origin |
| Entrez Gene | 10590 |
|---|
Application
Western blot analysis of SCGN expression in non-transfected: (A) and mouse SCGN transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of SCGN of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
