Application
Western blot analysis of SMYD2 expression in Hep G2 whole cell lysate.Application
Western blot analysis of SMYD2 expression in non-transfected (A) and human SMYD2 transfected (B) 293 whole cell lysates.| Product Name | SMYD2 Antibody (Y-22) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of SMYD2 of human origin by WB, IP and ELISA |
| Modification Notes | SMYD2 (SET and MYND domain containing 2), also known as KMT3C, HSKM-B or ZMYND14, is a 433 amino acid protein that contains one SET domain and one MYND-type zinc finger. Expressed at high levels in liver, heart, kidney, ovary and brain, SMYD2 functions as a lysine methyltransferase that, via methylation of p53, may play a role in repressing p53-mediated transcriptional regulation. The gene encoding MSYD2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of SMYD2 of human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of SMYD2 of human origin by WB, IP and ELISA |
| Entrez Gene | 56950 |
|---|
Application
Western blot analysis of SMYD2 expression in Hep G2 whole cell lysate.
Application
Western blot analysis of SMYD2 expression in non-transfected (A) and human SMYD2 transfected (B) 293 whole cell lysates.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
