epitope mapping within an internal region of LNX3 of human origin
Modification Notes
The eukaryotic PDZ domain is a multifunctional protein-protein interacting motif that is found in a variety of proteins and is involved in both the clustering of signaling molecules and the organization of protein networks. LNX3 (ligand of Numb protein X 3), also known as PDZRN3 (PDZ domain containing ring finger 3) or SEMCAP3 (semaphorin cytoplasmic domain-associated protein 3), is a 1,066 amino acid protein that contains one TRAF-type zinc finger, one RING-type zinc finger and two PDZ domains. Expressed in a variety of tissues, LNX3 interacts with neuroligin 1 and ephrin-B2 and may exhibit tumor suppressive activity in ovarian serous papillary tumors. Multiple isoforms of LNX3 exist due to alternative splicing events.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of LNX3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with LNX1, LNX2 or LNX4 also reactive with additional species, including canine and bovine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of LNX3 of human origin
Tissue Specificity
epitope mapping within an internal region of LNX3 of human origin
Western blot analysis of LNX3 expression in HeLa whole cell lysate.
Application Notes
recommended for detection of LNX3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with LNX1, LNX2 or LNX4 also reactive with additional species, including canine and bovine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.