| Product Name | CdcA1 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-300 mapping at the N-terminus of CdcA1 of human origin |
| Modification Notes | Kinetochores play an essential role in chromosome segregation by forming dynamic connections with spindle microtubules. Cell division associated 1 (CdcA1) is a member of the evolutionarily conserved centromere protein complex along with kinetochore associated 2 (KNTC2), and these two proteins are involved in the regulation of cell-cycle progression. The novel human cell cycle genes CdcA1 through CdcA8 are co-expressed with the well-known cell cycle genes including Cdc2, Cdc7, Cdc23, cyclin, and MCAK. Both CdcA1 and KNTC2 are implicated in non-small cell lung carcinomas (NSCLC), and selective suppression of CdcA1 or KNTC2 activity and/or inhibition of the CdcA1-KNTC2 complex formation may be a promising therapeutic target for treatment of lung cancers. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CdcA1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-300 mapping at the N-terminus of CdcA1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-300 mapping at the N-terminus of CdcA1 of human origin |
| Entrez Gene | 83540 |
|---|
| Application Notes | recommended for detection of CdcA1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
