Application
Western blot analysis of TET3 expression in non-transfected: (A) and human TET3 transfected: (B) 293T whole cell lysates.| Product Name | TET3 Antibody (T-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | TET3 (tet oncogene family member 3) is a 1,660 amino acid protein that belongs to the TET family and is expressed in both fetal and adult brain, as well as in muscle, colon and adrenal gland tissue. Existing as multiple alternatively spliced isoforms, TET3 may play a role in myeloid malignancies and overall tumor formation and metastasis. The gene encoding TET3 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alström syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TET3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with TET1 or TET2 also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of TET3 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of TET3 of human origin |
| Entrez Gene | 200424 |
|---|
Application
Western blot analysis of TET3 expression in non-transfected: (A) and human TET3 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of TET3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with TET1 or TET2 also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
