Application
Western blot analysis of kleisin β expression in HeLa whole cell lysate.Application
Western blot analysis of kleisin β expression in Hep G2 whole cell lysate.| Product Name | kleisin β Antibody (D-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Chromosome formation and subsequent function require the activity of two condensin complexes, namely condensin I and condensin II, both of which are crucial for proper mitotic chromosome assembly and segregation. Kleisin ∫, also known as NCAPH2 (non-SMC condensin II complex, subunit H2) or CAPH2, is a 605 amino acid protein that localizes to the nucleus and is specifically distributed along the arms of assembled chromosomes. Existing as a component of the condensin II complex, kleisin ∫ functions as a regulatory protein that assists in establishing mitotic chromosome architecture, possibly by providing an increased level of organization and rigidity to formed chromosomes. In response to DNA damage, kleisin ∫ is subject to phosphorylation by ATM or ATR. Multiple isoforms of kleisin ∫ exist due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of kleisin &beta of human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of kleisin β of human origin by WB, IP and ELISA |
| Entrez Gene | 29781 |
|---|
Application
Western blot analysis of kleisin β expression in HeLa whole cell lysate.
Application
Western blot analysis of kleisin β expression in Hep G2 whole cell lysate.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
