| Product Name | Myosin XVI Antibody (L-19) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Myosins are highly conserved, ubiquitously expressed proteins that interact with Actin to generate the force for cellular movements. The human genome encodes over 40 different Myosin genes which are divided into distinct classes, the most notable of which are the conventional Myosins (class II) and the unconventional Myosins (classes I and III through XVIII). Myosin XVI, also known as MYO16 or MYR8, is a 1,858 amino acid protein that localizes to the cytoplasm and contains one IQ domain, two myosin head-like domains and seven ANK repeats. Existing as an unconventional Myosin, Myosin XVI is involved in intracellular movements related to Actin filaments and is thought to interact specifically with PP1å and PP1©, possibly playing a role in PP1-associated brain development. Multiple isoforms of Myosin XVI exist due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of Myosin XVI of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other Myosin family members | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of Myosin XVI of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of Myosin XVI of human origin |
| Entrez Gene | 23026 |
|---|
| Application Notes | recommended for detection of Myosin XVI of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other Myosin family members |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
