Application
Western blot analysis of ZnT-9 expression in Hep G2 whole cell lysate.Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human liver tissue showing cytoplasmic localization.| Product Name | ZnT-9 Antibody (E-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Zinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions, including acting as a cofactor for numerous enzymes and transcription factors and as a neuroregulator. The zinc transporter (ZnT) or solute carrier 30(SLC30) family regulates the supply of zinc within cells, and its members are characterized by containing six membrane-spanning domains, a large histidine-rich intracellular loop, and a C-terminal tail. ZnT proteins also belong to the cation diffusion facilitator (CDF) transporter family of metal ion transporters. ZnT-9, also known as HUEL (human embryonic lung protein), GAC63 (GRIP1-associated coactivator 1) or SLC30 member 9, displays ubiquitous expression in fetal and adult tissues as well as cancer cell lines. ZnT-9 localizes to the cytoplasm and is translocated to the nucleus during S phase. ZnT-9 has the lowest homology with the other zinc transporters and may function as a DNA-binding protein. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of ZnT-9 of h and r origin by WB IP IF IHC(P) and ELISA also reactive with additional species including canine |
|---|---|
| Tissue Specificity | recommended for detection of ZnT-9 of h and r origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including canine |
| Entrez Gene | 10463 |
|---|
Application
Western blot analysis of ZnT-9 expression in Hep G2 whole cell lysate.
Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human liver tissue showing cytoplasmic localization.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
