The bromodomain is an approximately 70 amino acid region that is found in a variety of proteins and is thought to be involved in protein-proteins interactions and transcriptional activation. BRD9 (Bromodomain-containing protein 9), also known as PRO9856 or LAVS3040, is a 501 amino acid protein that contains one bromodomain and may be involved in various protein interactions throughout the cell. The gene encoding BRD9 maps to chromosome 5 and is expressed as four isoforms due to alternative splicing events. With 181 million base pairs encoding around 1,000 genes, chromosome 5 comprises about 6% of human genomic DNA. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm on chromosome 5 is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
recommended for detection of BRD9 of mouse, rat, human and canine origin by WB, IP and ELISA: