Application
Western blot analysis of IF-αR2 expression in HEK293 (A), Jurkat (B), K-562 (C), Hep G2 (D) and Caco-2 (E) whole cell lysates.| Product Name | IFN-α/βRβ Antibody (P-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an extracellular domain of IFN-α/βRβ of human origin |
| Modification Notes | The type I interferons, IFN-å and IFN-∫, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-å and IFN-∫ appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-©) binds to a distinct receptor. This distinct receptor, IFN-åR, is only weakly responsive to type I interferons, in contrast to IFN-å/∫R, which binds to and responds effectively to IFN-∫ and to several of the IFN-å subtypes. IFN-å/∫R is expressed as two alternatively spliced transcripts, designated IFN-å/∫Rå (IFN-å/∫R1) and IFN-å/∫R∫ (IFN-å/∫R2), both of which are involved in signal transduction and ligand binding. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of IFN-α/βRβ of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an extracellular domain of IFN-&alpha /&beta R&beta of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an extracellular domain of IFN-α/βRβ of human origin |
| Entrez Gene | 3455 |
|---|
Application
Western blot analysis of IF-αR2 expression in HEK293 (A), Jurkat (B), K-562 (C), Hep G2 (D) and Caco-2 (E) whole cell lysates.| Application Notes | recommended for detection of IFN-α/βRβ of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
