epitope mapping within an internal region of EURL of human origin
Modification Notes
First isolated in Gallus gallus retina and lens, EURL (early undifferentiated retina and lens), also known as C21orf91 of YG81, is a 297 amino acid protein that contains a putative carboxy-terminal coiled-coil domain. With highest expression in embryonic dorsal retina and, during later embryonic stages, the anterior epithelial cells of the lens, it is suspected that EURL may play a role in cell determination and differentiation. The gene encoding EURL maps to the long arm of chromosome 21, which houses approximately 300 genes and comprises nearly 1.5% of the human genome. Chromosome 21-associated disorders include Alzheimer's Disease, amyotrophic lateral sclerosis and, most notably, Down Syndrome (also known as trisomy 21).
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of EURL of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of EURL of human origin
Tissue Specificity
epitope mapping within an internal region of EURL of human origin
Western blot analysis of EURL expression in non-transfected: (A) and human EURL transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of EURL of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.