Application
Western blot analysis of EURL expression in non-transfected: (A) and human EURL transfected: (B) 293T whole cell lysates and A-431 nuclear extract (C).| Product Name | EURL Antibody (K-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the C-terminus of EURL of human origin |
| Modification Notes | First isolated in Gallus gallus retina and lens, EURL (early undifferentiated retina and lens), also known as C21orf91 of YG81, is a 297 amino acid protein that contains a putative carboxy-terminal coiled-coil domain. With highest expression in embryonic dorsal retina and, during later embryonic stages, the anterior epithelial cells of the lens, it is suspected that EURL may play a role in cell determination and differentiation. The gene encoding EURL maps to the long arm of chromosome 21, which houses approximately 300 genes and comprises nearly 1.5% of the human genome. Chromosome 21-associated disorders include Alzheimer's Disease, amyotrophic lateral sclerosis and, most notably, Down Syndrome (also known as trisomy 21). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of EURL of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the C-terminus of EURL of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the C-terminus of EURL of human origin |
| Entrez Gene | 54149 |
|---|
Application
Western blot analysis of EURL expression in non-transfected: (A) and human EURL transfected: (B) 293T whole cell lysates and A-431 nuclear extract (C).| Application Notes | recommended for detection of EURL of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
